All Notebooks | Help | Support | About
31st October 2013 @ 10:12

Started 20:30

To a well stirred solution of AEW 95-1 (500 mg,  1.94 mmol) in CH2Cl2 (15 mL) was added PhI(OAc)2 (625 mg, 1.94 mmol) and the resulting reaction mixture was stirred at room temperature for 1 h.

Solvent was evaporated in vacuo.The crude residue was purified by column chromatography (using silica gel 100-200 and gradient elution of 100% EA) to afford the 

 

Data:

 

Hazard and Risk Assessment:

See 4-(5-chloro-[1,2,4]triazolo[4,3-a]pyrazin-3-yl)benzonitrile (AEW 97-1) 

InChi:

InChI=1S/C12H8ClN5/c13-11-7-15-8-12(17-11)18-16-6-10-3-1-9(5-14)2-4-10/h1-4,6-8H,(H,17,18)/b16-6+

to

InChI=1S/C12H6ClN5/c13-10-6-15-7-11-16-17-12(18(10)11)9-3-1-8(5-14)2-4-9/h1-4,6-7H

Linked Posts
This post is linked by: