All Notebooks | Help | Support | About
25th September 2012 @ 06:16
Reaction Scheme

Pyrrole (1 g, 4.3 mmol, 1.0 equiv.) was dissolved in DMF (23 mL) at room temperature and then solid potassium carbonate (1.19 g, 6.0 mmol, 2 equiv.) added in two portions. Reaction mixture stirred at room temp. for 15 minutes and then 2-bromoacetamide (710 mg, 5.0 mmol, 1.2 equiv.) was added in a single portion and the reaction mixture stirred at room temperature for 1.5 hours. TLC analysis indicated product formation along with starting material.
Reaction mixture stirred for a further 1.5 h at room temperature.

TLC (100% EtOAc, stained with vanillin) after 1.5 h:
AEW 5-4 1.5 h.jpg
Linked Posts
This post is linked by:
Attached Files
AEW 5-4 1.5 h.jpg
Comments
Re: Ester Synthesis (AEW 5-4) by OSDD Malaria
25th January 2014 @ 11:58
OSM-S-5