All Notebooks | Help | Support | About
This is a previous version of this entry. To view the latest click here. or to view all revisions click here.
13th July 2012 @ 02:10
Coupling of 4-F aryl pyrrole acid chloride and secondary amine side chain PMY 53-2.


Reaction Start Time: 10.30 13/07/12
JRC 2-1 (250 mg, 1.1 mmol, 1 equiv.) was stirred in PhMe (2 mL) at room temperature. Thionyl chloride (0.16 mL, 2.1 mmol, 2 equiv.) was added.

See also:
Hydrogenolysis of benzyl protected amine PMY 51-2 (PMY 53-2)
Hydrolysis of Ethyl 1-(4-fluorophenyl)-2,5-dimethyl-1H-pyrrole-3-carboxylate (JRC 2-1)
Synthesis of TCMDC-123812 via acid chloride (PMY 10-6)

Risk and Hazard Assessment:
See: Synthesis of TCMDC-123812 via acid chloride (PMY 10-2)
Attached Files