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28th February 2014 @ 05:13
Osm: OSM-S-171_To_OSM-S-180

OSM-S-174

Original Sources

Nucleophilic Displacement of MNR99 with 1-Methylpiperazine to give MNR125-1

Synthesis of 4-(4-Methylpiperazin-1-yl)thieno[3,2-d]pyrimidine (AEW 55-1)

Repeat Synthesis of 4-(4-Methylpiperazin-1-yl)thieno[3,2-d]pyrimidine (AEW 55-2)

Biological Evaluation

N/A

Synonyms

MNR 125, AEW 55

 

CN(CC1)CCN1C2=NC=NC3=C2SC=C3

InChI=1S/C11H14N4S/c1-14-3-5-15(6-4-14)11-10-9(2-7-16-10)12-8-13-11/h2,7-8H,3-6H2,1H3

UFWRIHSVBLJCSP-UHFFFAOYSA-N

4-(4-methylpiperazin-1-yl)thieno[3,2-d]pyrimidine

Attached Files
28th February 2014 @ 03:48
Osm: OSM-S-171_To_OSM-S-180

OSM-S-173

Original Sources

Synthesis of N,N-dimethyl-4-bromobenzenesulfonamide - MNR123-1 (Test reaction) 

Biological Evaluation

N/A

Synonyms

MNR 123

 

BrC1=CC=C(S(=O)(N(C)C)=O)C=C1

InChI=1S/C8H10BrNO2S/c1-10(2)13(11,12)8-5-3-7(9)4-6-8/h3-6H,1-2H3

NQAUNPZZVCXYEJ-UHFFFAOYSA-N

4-bromo-N,N-dimethylbenzenesulfonamide

Attached Files
28th February 2014 @ 03:12
Osm: OSM-S-171_To_OSM-S-180

OSM-S-172

Original Sources

Synthesis of 4-methoxythieno[3,2-d]pyrimidine from MNR-89-2 (AEW 52-1)

Biological Evaluation

Synonyms

AEW 52

 

COC1=NC=NC2=C1SC=C2

InChI=1S/C7H6N2OS/c1-10-7-6-5(2-3-11-6)8-4-9-7/h2-4H,1H3

YDKUAOWCMDNAEX-UHFFFAOYSA-N

4-methoxythieno[3,2-d]pyrimidine

Attached Files
28th February 2014 @ 00:47
Osm: OSM-S-161_To_OSM-S-170

OSM-S-170

Original Sources

Synthesis of 2-((6-bromothieno[3,2-d]pyrimidin-4-yl)oxy)-N,N-dimethylethanamine (MJT 16-1)

Biological Evaluation

N/A

Synonyms

MJT 16

 

BrC1=CC2=NC=NC(OCCN(C)C)=C2S1

InChI=1S/C10H12BrN3OS/c1-14(2)3-4-15-10-9-7(12-6-13-10)5-8(11)16-9/h5-6H,3-4H2,1-2H3

SVRSGHTXGBHHFG-UHFFFAOYSA-N

2-((6-bromothieno[3,2-d]pyrimidin-4-yl)oxy)-N,N-dimethylethan-1-amine

Attached Files