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27th March 2013 @ 00:14
Osm: OSM-S-51_to_OSM-S-60

OSM-S-60

Original Sources

Reductive amination of pyrrole aldehyde with crude PMY 53-2 (PMY 56-1)

Synthesis of 2-(((1-(4-fluorophenyl)-2,5-dimethyl-1H-pyrrol-3-yl)methyl)(methyl)amino)acetamide (AEW 83-1)

Biological Data

3D7 - Avery - Preliminary Results for Phase 1 or Round 3 of Screening

Synonyms

PMY 56, AEW 83

FC(C=C1)=CC=C1N2C(C)=C(CN(C)CC(N)=O)C=C2C

InChI=1S/C16H20FN3O/c1-11-8-13(9-19(3)10-16(18)21)12(2)20(11)15-6-4-14(17)5-7-15/h4-8H,9-10H2,1-3H3,(H2,18,21)

GTOBCWQFLJRCDF-UHFFFAOYSA-N

2-(((1-(4-fluorophenyl)-2,5-dimethyl-1H-pyrrol-3-yl)methyl)(methyl)amino)acetamide

Attached Files
27th March 2013 @ 00:13
Osm: OSM-S-51_to_OSM-S-60


OSM-S-59

Original Sources

Coupling of crude PMY 53-2 and pyrrole acid chloride (PMY 55-1)

 

Biological Data

3D7 - Avery - Preliminary Results for Phase 1 or Round 3 of Screening

Synonyms

PMY 55, AEW 60

FC(C=C1)=CC=C1N2C(C)=C(C(N(C)CC(N)=O)=O)C=C2C

InChI=1S/C16H18FN3O2/c1-10-8-14(16(22)19(3)9-15(18)21)11(2)20(10)13-6-4-12(17)5-7-13/h4-8H,9H2,1-3H3,(H2,18,21)

HJRHAMSFPNSXOR-UHFFFAOYSA-N

N-(2-amino-2-oxoethyl)-1-(4-fluorophenyl)-N,2,5-trimethyl-1H-pyrrole-3-carboxamide

Attached Files
26th March 2013 @ 07:20
Osm: OSM-S-51_to_OSM-S-60

OSM-S-57

Original Sources

Synthesis of pyrazole analogue of TCMDC-123812 (PMY 50-1)

Synthesis of 2-amino-2-oxoethyl 5-methyl-1-phenyl-1H-pyrazole-4-carboxylate (SBHK-523).

Biological Data

3D7 - Avery - Preliminary Results for Phase 1 or Round 3 of Screening

Synonyms

PMY 50, SBHK-523

O=C(OCC(N)=O)C1=C(C)N(N=C1)C2=CC=CC=C2

InChI=1S/C13H13N3O3/c1-9-11(13(18)19-8-12(14)17)7-15-16(9)10-5-3-2-4-6-10/h2-7H,8H2,1H3,(H2,14,17)

FIEILXFXISZANS-UHFFFAOYSA-N

2-amino-2-oxoethyl 5-methyl-1-phenyl-1H-pyrazole-4-carboxylate

Attached Files