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2nd August 2014 @ 03:49
Osm: OSM-S-231_to_OSM-S-240

OSM-S-240
Context

OSM Series 1

Original Sources

Synthesis of ether-linked analogue of TCMDC-123794 (PMY 17-1)

Synthesis of ether-linked analogue of TCMDC-123794 (PMY 17-2)

Synthesis of ether-linked analogues of TCMDC-123812 and TCMDC-123794 (PMY 19-1)

Biological Data

N/A

Synonyms

PMY 17, PMY 19

FC1=CC=C(N2C(C)=CC(COCC(N(C3=C(C)N(C)N(C4=CC=CC=C4)C3=O)[H])=O)=C2C)C=C1

InChI=1S/C26H27FN4O3/c1-17-14-20(18(2)30(17)22-12-10-21(27)11-13-22)15-34-16-24(32)28-25-19(3)29(4)31(26(25)33)23-8-6-5-7-9-23/h5-14H,15-16H2,1-4H3,(H,28,32)

JYAOUVHBKPOGIT-UHFFFAOYSA-N

N-(1,5-dimethyl-3-oxo-2-phenyl-2,3-dihydro-1H-pyrazol-4-yl)-2-((1-(4-fluorophenyl)-2,5-dimethyl-1H-pyrrol-3-yl)methoxy)acetamide

Literature

Attached Files
2nd August 2014 @ 03:37
Osm: OSM-S-231_to_OSM-S-240

OSM-S-239
Context

OSM Series 1


Original Sources

Esterification with benzyl bromide (AEW 8-1)

Biological Data

N/A

Synonyms

AEW 8

FC1=CC=C(N2C(C)=CC(COCC3=CC=CC=C3)=C2C)C=C1

InChI=1S/C20H20FNO/c1-15-12-18(14-23-13-17-6-4-3-5-7-17)16(2)22(15)20-10-8-19(21)9-11-20/h3-12H,13-14H2,1-2H3

RAZLQWCELPTYIL-UHFFFAOYSA-N

3-((benzyloxy)methyl)-1-(4-fluorophenyl)-2,5-dimethyl-1H-pyrrole

Literature

Attached Files
2nd August 2014 @ 03:04
Osm: OSM-S-231_to_OSM-S-240

OSM-S-238
Context

OSM Series 1

Original Sources

Synthesis of 2-((1-(4-fluorophenyl)-2,5-dimethyl-1H-pyrrol-3-yl)methoxy)acetonitrile (AEW 28-1)

Synthesis of 2-((1-(4-fluorophenyl)-2,5-dimethyl-1H-pyrrol-3-yl)methoxy)acetonitrile (AEW 28-2)

Biological Data

N/A

Synonyms

AEW 28

FC1=CC=C(N2C(C)=CC(COCC#N)=C2C)C=C1

InChI=1S/C15H15FN2O/c1-11-9-13(10-19-8-7-17)12(2)18(11)15-5-3-14(16)4-6-15/h3-6,9H,8,10H2,1-2H3

MVFLXMHVIRLBLD-UHFFFAOYSA-N

2-((1-(4-fluorophenyl)-2,5-dimethyl-1H-pyrrol-3-yl)methoxy)acetonitrile


Literature

Attached Files
2nd August 2014 @ 02:57
Osm: OSM-S-231_to_OSM-S-240

OSM-S-237
Context

OSM Series 1

Original Sources

Attempted 1-Pot Synthesis of Ether MNR98-1

Attempted Solvent Free, 1-Pot Synthesis of Ether MNR98-2

Biological Data

N/A

Synonyms

MNR 98

FC1=CC=C(N2C(C)=CC(COCC(OC)=O)=C2C)C=C1

InChI=1S/C16H18FNO3/c1-11-8-13(9-21-10-16(19)20-3)12(2)18(11)15-6-4-14(17)5-7-15/h4-8H,9-10H2,1-3H3

LKHKYXZKZBNTBU-UHFFFAOYSA-N

methyl 2-((1-(4-fluorophenyl)-2,5-dimethyl-1H-pyrrol-3-yl)methoxy)acetate

Literature

Attached Files
2nd August 2014 @ 02:44
Osm: OSM-S-231_to_OSM-S-240

OSM-S-236
Context

OSM Series 1 ("the ether compound")


Original Sources

Synthesis of ether-linked analogue of TCMDC-123812 (PMY 37-1)

Synthesis of ether-linked analogue of TCMDC-123812 (PMY 37-2)

Synthesis of ether-linked analogue of TCMDC-123812 (PMY 37-3)

Synthesis of ether-linked analogue of TCMDC-123812 (AEW4-1)

Synthesis of ether-linked analogue of TCMDC-123812 (AEW4-2)

Synthesis of ether-linked analogue of TCMDC-123812 (AEW4-3)

Synthesis of ether-linked analogue of TCMDC-123812 (AEW4-4)

Synthesis of ether-linked analogue of TCMDC-123812 (AEW4-5)

Synthesis of ether-linked analogue of TCMDC-123812 (AEW4-6)

Synthesis of ether-linked analogue of TCMDC-123812 (AEW4-7)

Ester Formation (AEW 4-8)

Ether Synthesis (AEW 4-9)

Ester Synthesis (AEW 4-10)

Reduction of 2-amino-2-oxoethyl 1-(4-fluorophenyl)-2,5-dimethyl-1H-pyrrole-3-carboxylate (AEW 23-1)

Reduction of 2-amino-2-oxoethyl 1-(4-fluorophenyl)-2,5-dimethyl-1H-pyrrole-3-carboxylate (AEW 23-2)

Reduction of 2-amino-2-oxoethyl 1-(4-fluorophenyl)-2,5-dimethyl-1H-pyrrole-3-carboxylate (AEW 23-3)

Biological Data

N/A

Synonyms

PMY 37, AEW 4, AEW 23

FC1=CC=C(N2C(C)=CC(COCC(N)=O)=C2C)C=C1

InChI=1S/C15H17FN2O2/c1-10-7-12(8-20-9-15(17)19)11(2)18(10)14-5-3-13(16)4-6-14/h3-7H,8-9H2,1-2H3,(H2,17,19)

UFAJOCCDASJXPL-UHFFFAOYSA-N

2-((1-(4-fluorophenyl)-2,5-dimethyl-1H-pyrrol-3-yl)methoxy)acetamide


Literature

Attached Files