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4th April 2013 @ 06:21


 

Reaction start time: 6:00 PM EST 19/3/13

Crude MD 28-3 was dissolved in pyridine (10 ml) and mixed with Glycine methyl ester (0.13 g, 0.10 mmol, 5 eq.), which was was stirred overnight at room temperature. The reaction was then concentrated under reduced pressure to give the crude product (30 mg). The crude product was columned with 50:50, ethyl acetate:hexane solvent mixture to give the purified product (15 mg).


NMR: 

MD 29-1.pdf
MD_29-1_silica.rar

 

Risk and hazard assessment:

Same as second half of Synthesis of 2-(1-(4-fluorophenyl)-2,5-dimethyl-1H-pyrrole-3-sulfonamido)acetamide (MD 26-2)

Attached Files
MD 29-1.png
MD 29-1.pdf
MD_29-1_silica.rar