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3rd December 2012 @ 03:04

 



Reaction start time: 8:10 PM EST 29/11/12
MD 17-1 (0.76 g, ) was dissolved in EtOH (35 mL), 20% NaOH (3.4 mL, mmol, 9 equiv.) and the mixture was stirred at room temperature for 1.5 hours after which HCl (3 M, 10 mL, ) was added and the EtOH was removed under reduced atmosphere.

See also:
Synthesis of 1-ethoxy-1-oxopropan-2-yl 1-(4-fluorophenyl)-2,5-dimethyl-1H-pyrrole-3-carboxylate through ester synthesis (MD 17-1)

Risk and Hazard assessment:
Same as Hydrolysis of Ethyl-2-bromopropionate (MD 16-1)

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