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25th October 2012 @ 01:03
Synthesis of 1-amino-2-methyl-1-oxopropan-2-yl 1-(4-fluorophenyl)-2,5-dimethyl-1H-pyrrole-3-carboxylate in the presence of TEMPO to explore if the reaction occurs via a radical intermediate.

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Reaction start time: EST 25/10/12

See also:
Synthesis of 1-amino-2-methyl-1-oxopropan-2-yl 1-(4-fluorophenyl)-2,5-dimethyl-1H-pyrrole-3-carboxylate (MD 5-3)
Upscaled synthesis of 1-amino-2-methyl-1-oxopropan-2-yl 1-(4-fluorophenyl)-2,5-dimethyl-1H-pyrrole-3-carboxylate MD (5-2)
Synthesis of 1-amino-2-methyl-1-oxopropan-2-yl 1-(4-fluorophenyl)-2,5-dimethyl-1H-pyrrole-3-carboxylate MD (5-1)

Risk and Hazard assessment:
Same as Synthesis of 1-amino-2-methyl-1-oxopropan-2-yl 1-(4-fluorophenyl)-2,5-dimethyl-1H-pyrrole-3-carboxylate MD (5-1) except with addition of 2,2,6,6-Tetramethyl-1-piperidinyloxy (TEMPO).
Hazard statements for TEMPO: Causes severe skin burns and eye damage.
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