Biological Evaluation of Compounds

Data derived from pre-OSM work on Series 4 amides. Was originally posted here, but posted here again as may be more suitable grouped with biological data.

Original spreadsheet:

Wiki summary here.

Chemdraw file

Picture file

Strings:

MMV668958    N1=CC2=NN=C(N2C(=C1)C(=O)NCc1cc(ccc1)Cl)c1ccc(cc1)OC(F)F
MMV669000    N1=CC2=NN=C(N2C(=C1)C(=O)N1Cc2c(cccc2)C1)c1ccc(cc1)OC(F)F
MMV669001    N1=CC2=NN=C(N2C(=C1)C(=O)NCc1ccc(cc1)Cl)c1ccc(cc1)OC(F)F
MMV669002    N1=CC2=NN=C(N2C(=C1)C(=O)NCc1ccccc1Cl)c1ccc(cc1)OC(F)F
MMV669003    N1=CC2=NN=C(N2C(=C1)C(=O)NCC1CCOCC1)c1ccc(cc1)OC(F)F
MMV669010    N1=CC2=NN=C(N2C(=C1)C(=O)N1CCN(c2ncccc2)CC1)c1ccc(cc1)OC(F)F
MMV669011    N1=CC2=NN=C(N2C(=C1)C(=O)NCCN1CCOCC1)c1ccc(cc1)OC(F)F
MMV669022    N1=CC2=NN=C(N2C(=C1)C(=O)N1CCCC1)c1ccc(cc1)OC(F)F
MMV669104    N1(CCCC1c1ccccc1)C(=O)C1=CN=CC2=NN=C(N12)c1ccc(cc1)OC(F)F
MMV669023    N1(CCN(CC1)S(=O)(=O)C)C(=O)C1=CN=CC2=NN=C(N12)c1ccc(cc1)OC(F)F
MMV669020    N1(CCOCC1)C(=O)C1=CN=CC2=NN=C(N12)c1ccc(cc1)OC(F)F
MMV669024    N([C@H](c1ccccc1)C)C(=O)C1=CN=CC2=NN=C(N12)c1ccc(cc1)OC(F)F
MMV669021    N([C@@H](c1ccccc1)C)C(=O)C1=CN=CC2=NN=C(N12)c1ccc(cc1)OC(F)F
MMV669026    n1c(cccc1)NC(=O)C1=CN=CC2=NN=C(N12)c1ccc(cc1)OC(F)F
MMV669027    N(CCc1ccccc1)C(=O)C1=CN=CC2=NN=C(N12)c1ccc(cc1)OC(F)F
MMV669105    Clc1cc(ccc1)CN(C)C(=O)C1=CN=CC2=NN=C(N12)c1ccc(cc1)OC(F)F
MMV669543    n12c(cncc1nnc2c3ccc(cc3)OC(F)F)C(=O)NCc4ccc(c(c4)F)F
MMV669542    n12c(cncc1nnc2c3ccc(cc3)OC(F)F)C(=O)Nc4cccc(c4)Cl
MMV670246    c1ncc2nnc(n2c1C(Nc1ccc(cc1)Cl)=O)c1ccc(cc1)OC(F)F
MMV669849    c1ncc2nnc(n2c1C(Nc1ccc(cc1)F)=O)c1ccc(cc1)OC(F)F
MMV669850    c1ncc2nnc(n2c1C(Nc1ccc(c(c1)F)F)=O)c1ccc(cc1)OC(F)F
MMV670767    c1ncc2n(c1C(=O)Nc1ccc(c(c1)Cl)F)c(nn2)c1ccc(cc1)OC(F)F
MMV670944    c1ncc2n(c1C(=O)Nc1ccnc(c1)C(F)(F)F)c(nn2)c1ccc(cc1)OC(F)F
MMV670768    c1ncc2n(c1C(=O)N1CCc3c1ccc(c3)F)c(nn2)c1ccc(cc1)OC(F)F
MMV671654    c1ncc2n(c1C(=O)Nc1ccc(cc1Cl)F)c(nn2)c1ccc(cc1)OC(F)F
MMV671676    c1c(c(ccc1Cl)Cl)CNC(c1cncc2n1c(nn2)c1ccc(cc1)OC(F)F)=O
MMV671677    c1c(c(c(cc1)C(F)(F)F)Cl)CNC(c1cncc2n1c(nn2)c1ccc(cc1)OC(F)F)=O