All Notebooks | Help | Support | About
21st November 2012 @ 03:31
Mnr: MNR51-60
See - Synthesis on JRC13-4
- Synthesis on JRC17-2

MNR60_scheme.png
MNR60-1_table.PNG

Hazard Assessment
HIRAC MNR58.pdf

Procedure

reaction on at 1600pm 21/11/12

JRC13-4 (0.1 g, 0.586 mmol) was dissolved in methanol (7 mL) and stirred at rt. To the stirring solution was added 2methylindole(0.115 g, 0.88 mmol). The resultant solution was stirred at rt for XX hours.

The reaction was then concentrated and extract xtracted with EtOAc (10 mL), washed with water (2 x 10 mL), organic dried over MgSO4 to yield a XXX

Frac 36-51 - 0.063 g, not SM or product

NMR

Fraction 21-30 - Starting material
mnr60-1_frac21-30_1H.pdf


Fraction 36-51 - Major spot
mnr60-1_frac36-51_conc_1H.pdf
mnr60-1_frac36-51_conc_13C.pdf
mnr60-1_frac36-51_conc.zip


JRC15-4
JRC15-4_1H.pdf
JRC15-4_13C.pdf
JRC15-4_conc.zip
Attached Files
21st November 2012 @ 03:27
Mnr: MNR51-60
See - Synthesis on JRC13-4
- Synthesis on JRC17-2

MNR59_scheme.png
MNR59-1_table.PNG

Hazard Assessment
HIRAC MNR58.pdf

Procedure

reaction on at 1600pm 21/11/12

JRC13-4 (0.1 g, 0.586 mmol) was dissolved in methanol (7 mL) and stirred at rt. To the stirring solution was added 2,5-dimethylpyrrole(0.09 mL, 0.88 mmol) dropwise. The resultant solution was stirred at rt for XX hours.

The reaction was then concentrated and extract xtracted with EtOAc (10 mL), washed with water (2 x 10 mL), organic dried over MgSO4 to yield a XXX
Attached Files
21st November 2012 @ 03:23
Mnr: MNR51-60
See - Synthesis on JRC13-4
- Synthesis on JRC17-2

MNR58_scheme.png
MNR58-1_table.PNG

Hazard Assessment
HIRAC MNR58.pdf

Procedure

reaction on at 1600pm 21/11/12

JRC13-4 (0.1 g, 0.586 mmol) was dissolved in methanol (7 mL) and stirred at rt. To the stirring solution was added pyrrole (0.061 mL, 0.88 mmol) dropwise. The resultant solution was stirred at rt for XX hours.

The reaction was then concentrated and extract xtracted with EtOAc (10 mL), washed with water (2 x 10 mL), organic dried over MgSO4 to yield a XXX

Frac 8-11 0.029 g - SM
Frac 26-50 0.062 g - not product, not SM

NMR

Fraction 8-11 - Starting material
mnr58-1_frac8-11_13C.pdf
mnr58-1_frac8-11_1H.pdf
mnr58-1_frac8-11_conc.zip


Fraction 26-50 - Major spot
mnr58-1_frac26-50_1H.pdf
mnr58-1_frac26-50_conc.zip
Attached Files