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26th March 2013 @ 07:11
Osm: OSM-S-51_to_OSM-S-60


OSM-S-52

Original Sources

Synthesis of near neighbour analogue from p-trifluoromethyl arylpyrrole and diphenyl thiazolidinone (ZYH 19-1)

Biological Data

3D7, K1 and HEK293 - Avery - Second Round of Evaluation by the Avery Lab

3D7 - Ralph - Second Round Biological evaluation by James Pham and Stuart Ralph

3D7 - GSK - Second Round of Evaluation by GSK Tres Cantos

GSK DHODH Assay

Synonyms

ZYH 19

CC(N1C2=CC=C(C(F)(F)F)C=C2)=CC(/C=C(C(N/3C4=CC=CC=C4)=O)\SC3=N/C5=CC=CC=C5)=C1C

InChI=1S/C29H22F3N3OS/c1-19-17-21(20(2)34(19)25-15-13-22(14-16-25)29(30,31)32)18-26-27(36)35(24-11-7-4-8-12-24)28(37-26)33-23-9-5-3-6-10-23/h3-18H,1-2H3/b26-18-,33-28+

SACGGTIRNSKYBF-USPGIJFQSA-N

(2Z,5Z)-5-((2,5-dimethyl-1-(4-(trifluoromethyl)phenyl)-1H-pyrrol-3-yl)methylene)-3-phenyl-2-(phenylimino)thiazolidin-4-one

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Attached Files
OSM-S-52.cdx
OSM-S-52.png