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26th March 2013 @ 07:09
Osm: OSM-S-41_to_OSM-S-50


OSM-S-50

Original Sources

Acetylation of para-methyl arylpyrrole near neighbour analogue (ZYH 17-1)

Resynthesis of (Z)-N-(5-((2,5-dimethyl-1-(p-tolyl)-1H-pyrrol-3-yl)methylene)-4-oxo-4,5-dihydrothiazol-2-yl)-N-phenylacetamide (AEW 79-1, OSM-S-50)

Biological Data

3D7, K1 and HEK293 - Avery - Second Round of Evaluation by the Avery Lab

3D7 - Ralph - Second Round Biological evaluation by James Pham and Stuart Ralph

3D7 - GSK - Second Round of Evaluation by GSK Tres Cantos

GSK DHODH Assay

Synonyms

ZYH 17, AEW 79

O=C(N=C(S/1)N(C2=CC=CC=C2)C(C)=O)C1=C\C3=C(C)N(C4=CC=C(C)C=C4)C(C)=C3

InChI=1S/C25H23N3O2S/c1-16-10-12-22(13-11-16)27-17(2)14-20(18(27)3)15-23-24(30)26-25(31-23)28(19(4)29)21-8-6-5-7-9-21/h5-15H,1-4H3/b23-15-

RZFIAJJLMRMIBB-HAHDFKILSA-N

(Z)-N-(5-((2,5-dimethyl-1-(p-tolyl)-1H-pyrrol-3-yl)methylene)-4-oxo-4,5-dihydrothiazol-2-yl)-N-phenylacetamide

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Attached Files
OSM-S-50.cdx
OSM-S-50.png