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26th March 2013 @ 06:36
Osm: OSM-S-41_to_OSM-S-50


OSM-S-42

Original Sources

Synthesis of acetonitrile substituted p-trifluoromethyl near neighbour analogue (ZYH 10-1)

Synthesis of acetonitrile substituted p-trifluoromethyl near neighbour analogue (ZYH 10-2)

Biological Data

3D7, K1 and HEK293 - Avery - Second Round of Evaluation by the Avery Lab

3D7 - Ralph - Second Round Biological evaluation by James Pham and Stuart Ralph

3D7 - GSK - Second Round of Evaluation by GSK Tres Cantos

GSK DHODH Assay

Synonyms

ZYH 10 (actually ZYH 10-2A)

CC(N1C2=CC=C(C(F)(F)F)C=C2)=C(/C=C(C(N/3CC#N)=O)\SC3=N/C4=CC=CC=C4)C=C1C

InChI=1S/C25H19F3N4OS/c1-16-14-18(17(2)32(16)21-10-8-19(9-11-21)25(26,27)28)15-22-23(33)31(13-12-29)24(34-22)30-20-6-4-3-5-7-20/h3-11,14-15H,13H2,1-2H3/b22-15-,30-24+

CYTCJKBOZWMCAR-DDABIZCTSA-N

2-((2Z,5Z)-5-((2,5-dimethyl-1-(4-(trifluoromethyl)phenyl)-1H-pyrrol-3-yl)methylene)-4-oxo-2-(phenylimino)thiazolidin-3-yl)acetonitrile

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Attached Files
OSM-S-42.cdx
OSM-S-42.png