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26th March 2013 @ 06:34
Osm: OSM-S-31_to_OSM-S-40


Original Sources

Synthesis of 3,5-bis(trifluoromethyl) arylpyrrole based near neighbour analogue (ZYH 7-1)

Synthesis of 3,5-bis(trifluoromethyl) arylpyrrole based near neighbour analogue (ZYH 7-2)

Biological Data

3D7, K1 and HEK293 - Avery - Second Round of Evaluation by the Avery Lab

3D7 - Ralph - Second Round Biological evaluation by James Pham and Stuart Ralph

3D7 - GSK - Second Round of Evaluation by GSK Tres Cantos

Metabolism - Metabolism and Solubility Results

Late stage gametocyte testing of a sample set of GSK-Arylpyrrole Series

GSK DHODH Assay

Synonyms

ZYH 7

CC1=CC(/C=C(C(N/2)=O)\SC2=N/C3=CC=CC=C3)=C(C)N1C4=CC(C(F)(F)F)=CC(C(F)(F)F)=C4

InChI=1S/C24H17F6N3OS/c1-13-8-15(9-20-21(34)32-22(35-20)31-18-6-4-3-5-7-18)14(2)33(13)19-11-16(23(25,26)27)10-17(12-19)24(28,29)30/h3-12H,1-2H3,(H,31,32,34)/b20-9-

GVGNOLWIUGQIHW-UKWGHVSLSA-N

(2Z,5Z)-5-((1-(3,5-bis(trifluoromethyl)phenyl)-2,5-dimethyl-1H-pyrrol-3-yl)methylene)-2-(phenylimino)thiazolidin-4-one

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