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26th March 2013 @ 06:33
Osm: OSM-S-31_to_OSM-S-40

OSM-S-38

Original Sources

Synthesis of p-trifluoromethyl arylpyrrole based near-neighbour analogue (ZYH 6-1)

Scale up of preparation of 4-trifluoromethyl arylpyrrole based near neighbour (ZYH 6-2)

Biological Data

3D7, K1 and HEK293 - Avery - Second Round of Evaluation by the Avery Lab

3D7 - Ralph - Second Round Biological evaluation by James Pham and Stuart Ralph

3D7 - GSK - Second Round of Evaluation by GSK Tres Cantos

Metabolism - Metabolism and Solubility Results

Late stage gametocyte testing of a sample set of GSK-Arylpyrrole Series

GSK DHODH Assay

Synonyms

ZYH 6

CC1=CC(/C=C(C(N/2)=O)\SC2=N/C3=CC=CC=C3)=C(C)N1C(C=C4)=CC=C4C(F)(F)F

InChI=1S/C23H18F3N3OS/c1-14-12-16(15(2)29(14)19-10-8-17(9-11-19)23(24,25)26)13-20-21(30)28-22(31-20)27-18-6-4-3-5-7-18/h3-13H,1-2H3,(H,27,28,30)/b20-13-

YBBWTVGRVHTTDD-MOSHPQCFSA-N

(2Z,5Z)-5-((2,5-dimethyl-1-(4-(trifluoromethyl)phenyl)-1H-pyrrol-3-yl)methylene)-2-(phenylimino)thiazolidin-4-one

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Attached Files
OSM-S-38.cdx
OSM-S-38.png