All Blogs | Help | Support | About
x This LabTrove instance has just been upgraded to 2.3, to see what new check out the documentation, http://www.labtrove.org/documentation/
26th March 2013 @ 05:20
Osm: OSM-S-1_to_OSM-S-10

OSM-S-8

Original Sources

Coupling of acid PMY 8-2 and 4-aminoantipyrine for a linker-less analogue of TCMDC-123794 (PMY 12-1)

Coupling of acid PMY 8-2 and 4-aminoantipyrine for a linker-less analogue of TCMDC-123794 (PMY 12-2)

Failed: Coupling of acid PMY 8-2 and 4-aminoantipyrine using EDC for a linker-less analogue of TCMDC-123794 (PMY 12-3)

Coupling of acid PMY 8-2 and 4-aminoantipyrine using T3P for a linker-less analogue of TCMDC-123794 (PMY 12-4)

Coupling of acid PMY 8-3 and 4-aminoantipyrine using T3P for a linker-less analogue of TCMDC-123794 (PMY 12-5)

Repeat synthesis of N-(1,5-dimethyl-3-oxo-2-phenyl-2,3-dihydro-1H-pyrazol-4-yl)-1-(4-fluorophenyl)-2,5-dimethyl-1H-pyrrole-3-carboxamide, OSM-S-8 (AEW 62-1)

Biological Data

3D7, K1 and HEK293 - Avery - Second Analysis of First Set of Compounds (Avery)

3D7 - GSK - Re-evaluation of TCMDC-123794, TCMDC-123812 and others by GSK Tres Cantos

3D7 - Ralph - Second Round Biological evaluation by James Pham and Stuart Ralph

GSK DHODH Assay

Synonyms

PMY 12, AEW 62

FC1=CC=C(N2C(C)=CC(C(NC3=C(C)N(C)N(C4=CC=CC=C4)C3=O)=O)=C2C)C=C1

InChI=1S/C24H23FN4O2/c1-15-14-21(16(2)28(15)19-12-10-18(25)11-13-19)23(30)26-22-17(3)27(4)29(24(22)31)20-8-6-5-7-9-20/h5-14H,1-4H3,(H,26,30)

NVKLEDPUHCCJRE-UHFFFAOYSA-N

N-(1,5-dimethyl-3-oxo-2-phenyl-2,3-dihydro-1H-pyrazol-4-yl)-1-(4-fluorophenyl)-2,5-dimethyl-1H-pyrrole-3-carboxamide

Linked Posts
This post is linked by:
Attached Files
OSM-S-8.cdx
OSM-S-8.png