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14th May 2012 @ 23:53
Biological testing of the 2nd round of compounds reported on 05/05/12 by James S. Pham from the University of Melbourne.

Visual summary of results and compound structures:
Visual Summary


Methods Overview:
"Compounds were tested for inhibition of Plasmodium falciparum growth using a SYBR green I fluorescence based assay. Dose response curves were generated comprising of 8 points using a 2-fold serial dilution for the maximum final concentration of 1000 nM. The lowest concentration tested was 7.81 nM."

Raw Data originally posted on Google+ along with a detailed method description and report.

Raw data and graphs in excel format:
Raw Data and Graphs


Compounds tested:
PMY 12-5, PMY 27-2, PMY 31-5, PMY 34-1, ZYH 3-1, ZYH 5-1, ZYH 6-1/6-2, ZYH 7-2, ZYH 10-2 A, ZYH 10-2 B, ZYH 12-1/12-2, ZYH 15-1, ZYH 16-1, ZYH 17-1, ZYH 18-1, ZYH 19-1, ZYH 22-3, ZYH 23-1

Analysis of the same compounds:
Second Round of Evaluation by GSK Tres Cantos
Second Round of Evaluation by the Avery Lab

Results largely consistent with above analyses.
Linked Posts
Attached Files
Raw Data and Graphs
Visual Summary